Sam and Dean answer a call on their dad's old cell phone, alerting them someone has broken into John's secret storage room in New York. They discover a cursed rabbit's foot has been stolen and call Bobby for help. He advises them to beware of the foot because anyone who touches it will receive an extreme amount of good luck, but once the foot is lost that person will die. Unfortunately, Sam has already handled the foot, which causes an overjoyed Dean to buy lottery tickets, but a female thief steals it from Sam causing his luck to plummet and putting his life in danger.