Cuban couple Esteban and his sick wife, Marina Hernandez, are pulled from the ocean during a dangerous rescue en route to the U.S. on a mission to reach Dr. House. Her detailed medical records from Cuba were lost during the rescue, so the team runs a series of tests to determine the extent of her heart condition. But when she gets worse, House wonders if someone on his staff made a mistake. Meanwhile, Foreman prepares to leave, and his departure shakes up the entire team with House firing Chase and Cameron resigning.